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Target
Wee1-like protein kinase
Ligand
BDBM43770
Substrate
n/a
Meas. Tech.
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation PubChem Bioassay (2008)[AID] 
Target
Name:
Wee1-like protein kinase
Synonyms:
Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN
Type:
PROTEIN
Mol. Mass.:
71599.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1445054
Residue:
646
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
  
Inhibitor
Name:
BDBM43770
Synonyms:
(3Z)-3-(2-oxidanylidene-2-thiophen-2-yl-ethylidene)-1,4-dihydroquinoxalin-2-one | (3Z)-3-(2-oxo-2-thiophen-2-ylethylidene)-1,4-dihydroquinoxalin-2-one | (3Z)-3-[2-keto-2-(2-thienyl)ethylidene]-1,4-dihydroquinoxalin-2-one | 3-[2-oxo-2-(2-thienyl)ethylidene]-3,4-dihydro-2(1H)-quinoxalinone | MLS000705005 | SMR000230609 | cid_5410433
Type:
Small organic molecule
Emp. Form.:
C14H10N2O2S
Mol. Mass.:
270.306
SMILES:
O=C(Cc1nc2ccccc2[nH]c1=O)c1cccs1
Structure:
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