Reaction Details Report a problem with these data
Target
Wee1-like protein kinase
Ligand
BDBM43774
Substrate
n/a
Meas. Tech.
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation PubChem Bioassay (2008)[AID] 
Target
Name:
Wee1-like protein kinase
Synonyms:
Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN
Type:
PROTEIN
Mol. Mass.:
71599.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1445054
Residue:
646
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
  
Inhibitor
Name:
BDBM43774
Synonyms:
MLS001017252 | N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]acetamide | N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]ethanamide | N-[4-[(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide | N-[4-[(E)-(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide | SMR000353528 | cid_220697
Type:
Small organic molecule
Emp. Form.:
C16H14N4OS
Mol. Mass.:
310.374
SMILES:
CC(=O)Nc1ccc(CN=Nc2nc3ccccc3s2)cc1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: