Reaction Details Report a problem with these data
Target
Wee1-like protein kinase
Ligand
BDBM43776
Substrate
n/a
Meas. Tech.
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation PubChem Bioassay (2008)[AID] 
Target
Name:
Wee1-like protein kinase
Synonyms:
Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN
Type:
PROTEIN
Mol. Mass.:
71599.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1445054
Residue:
646
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
  
Inhibitor
Name:
BDBM43776
Synonyms:
(5Z)-2-anilino-5-[(1-methyl-2-pyrrolyl)methylidene]-4-thiazolone | (5Z)-2-anilino-5-[(1-methylpyrrol-2-yl)methylene]-2-thiazolin-4-one | (5Z)-2-anilino-5-[(1-methylpyrrol-2-yl)methylidene]-1,3-thiazol-4-one | (5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-2-phenylazanyl-1,3-thiazol-4-one | 5-[1-(1-Methyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-[(E)-phenylimino]-thiazolidin-4-one | MLS000333177 | SMR000436531 | cid_941925
Type:
Small organic molecule
Emp. Form.:
C15H13N3OS
Mol. Mass.:
283.348
SMILES:
Cn1cccc1C=C1SC(Nc2ccccc2)=NC1=O |w:6.6,c:18|
Structure:
Search PDB for entries with ligand similarity: