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Target
Wee1-like protein kinase
Ligand
BDBM43777
Substrate
n/a
Meas. Tech.
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation PubChem Bioassay (2008)[AID] 
Target
Name:
Wee1-like protein kinase
Synonyms:
Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN
Type:
PROTEIN
Mol. Mass.:
71599.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1445054
Residue:
646
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
  
Inhibitor
Name:
BDBM43777
Synonyms:
2-(4-Methoxy-phenyl)-5-(4-methoxy-phenylamino)-oxazole-4-carbonitrile | 2-(4-methoxyphenyl)-5-(p-anisidino)oxazole-4-carbonitrile | 2-(4-methoxyphenyl)-5-[(4-methoxyphenyl)amino]-1,3-oxazole-4-carbonitrile | 5-(4-methoxyanilino)-2-(4-methoxyphenyl)-1,3-oxazole-4-carbonitrile | 5-(4-methoxyanilino)-2-(4-methoxyphenyl)-4-oxazolecarbonitrile | MLS000769368 | SMR000434102 | cid_950402
Type:
Small organic molecule
Emp. Form.:
C18H15N3O3
Mol. Mass.:
321.33
SMILES:
COc1ccc(Nc2oc(nc2C#N)-c2ccc(OC)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: