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Target
G2/mitotic-specific cyclin-B1
Ligand
BDBM43774
Substrate
n/a
Meas. Tech.
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay (2008)[AID] 
Target
Name:
G2/mitotic-specific cyclin-B1
Synonyms:
CCNB | CCNB1 | CCNB1_HUMAN
Type:
Enzyme Subunit
Mol. Mass.:
48340.95
Organism:
Homo sapiens (Human)
Description:
P14635
Residue:
433
Sequence:
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
  
Inhibitor
Name:
BDBM43774
Synonyms:
MLS001017252 | N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]acetamide | N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]ethanamide | N-[4-[(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide | N-[4-[(E)-(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide | SMR000353528 | cid_220697
Type:
Small organic molecule
Emp. Form.:
C16H14N4OS
Mol. Mass.:
310.374
SMILES:
CC(=O)Nc1ccc(CN=Nc2nc3ccccc3s2)cc1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: