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Target
Ephrin type-A receptor 4
Ligand
BDBM44425
Substrate
n/a
Meas. Tech.
Counter Screen for Placental Alkaline Phosphatase-based Assays Positives
IC50
>50000±0 nM
Citation
 PubChem, PC Counter Screen for Placental Alkaline Phosphatase-based Assays Positives PubChem Bioassay (2008)[AID] 
Target
Name:
Ephrin type-A receptor 4
Synonyms:
EPHA4_MOUSE | Eph receptor A4 | Epha4 | Sek | Sek1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
109812.17
Organism:
Mus musculus
Description:
gi_34328113
Residue:
986
Sequence:
MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDASCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV
  
Inhibitor
Name:
BDBM44425
Synonyms:
2-[4-(2-furoyl)-1,4-diazepan-1-yl]-6,8-dimethyl-quinoline-3-carbonitrile | 2-[4-(Furan-2-carbonyl)-[1,4]diazepan-1-yl]-6,8-dimethyl-quinoline-3-carbonitrile | 2-[4-(furan-2-carbonyl)-1,4-diazepan-1-yl]-6,8-dimethylquinoline-3-carbonitrile | 2-[4-(furan-2-ylcarbonyl)-1,4-diazepan-1-yl]-6,8-dimethyl-quinoline-3-carbonitrile | 2-[4-[2-furanyl(oxo)methyl]-1,4-diazepan-1-yl]-6,8-dimethyl-3-quinolinecarbonitrile | MLS000027925 | SMR000006854 | cid_648049
Type:
Small organic molecule
Emp. Form.:
C22H22N4O2
Mol. Mass.:
374.4357
SMILES:
Cc1cc(C)c2nc(N3CCCN(CC3)C(=O)c3ccco3)c(cc2c1)C#N
Structure:
Search PDB for entries with ligand similarity: