Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44537
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44537
Synonyms:
(2-methylbenzofuro[3,2-d]pyrimidin-4-yl)-(4-pyridyl)amine | 2-methyl-N-pyridin-4-yl-4-benzofuro[3,2-d]pyrimidinamine | 2-methyl-N-pyridin-4-yl-[1]benzofuro[3,2-d]pyrimidin-4-amine | MLS000041006 | SMR000044654 | cid_663838
Type:
Small organic molecule
Emp. Form.:
C16H12N4O
Mol. Mass.:
276.2927
SMILES:
Cc1nc(Nc2ccncc2)c2oc3ccccc3c2n1
Structure:
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