Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM43572
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
2471±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM43572
Synonyms:
(4'-amino-3,3'-diethoxy-4-biphenylyl)amine | 4-(4-amino-3-ethoxyphenyl)-2-ethoxyaniline | 4-(4-azanyl-3-ethoxy-phenyl)-2-ethoxy-aniline | MLS000065366 | SMR000079128 | [4-(4-amino-3-ethoxy-phenyl)-2-ethoxy-phenyl]amine | cid_974772
Type:
Small organic molecule
Emp. Form.:
C16H20N2O2
Mol. Mass.:
272.3422
SMILES:
CCOc1cc(ccc1N)-c1ccc(N)c(OCC)c1
Structure:
Search PDB for entries with ligand similarity: