Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44547
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44547
Synonyms:
2-N-(3-methoxyphenyl)-6-(3-methyl-1-benzofuran-2-yl)-1,3,5-triazine-2,4-diamine | MLS000559194 | N-(3-Methoxy-phenyl)-6-(3-methyl-benzofuran-2-yl)-[1,3,5]triazine-2,4-diamine | N2-(3-methoxyphenyl)-6-(3-methyl-1-benzofuran-2-yl)-1,3,5-triazine-2,4-diamine | N2-(3-methoxyphenyl)-6-(3-methyl-2-benzofuranyl)-1,3,5-triazine-2,4-diamine | SMR000149510 | [4-amino-6-(3-methylbenzofuran-2-yl)-s-triazin-2-yl]-(3-methoxyphenyl)amine | cid_1850707
Type:
Small organic molecule
Emp. Form.:
C19H17N5O2
Mol. Mass.:
347.3706
SMILES:
COc1cccc(Nc2nc(N)nc(n2)-c2oc3ccccc3c2C)c1
Structure:
Search PDB for entries with ligand similarity: