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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM30721
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
9978±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM30721
Synonyms:
6-chloranyl-4-phenyl-2-piperazin-1-yl-quinazoline | 6-chloro-4-phenyl-2-(1-piperazinyl)quinazoline | 6-chloro-4-phenyl-2-piperazin-1-ylquinazoline | 6-chloro-4-phenyl-2-piperazino-quinazoline | MLS000027613 | SMR000039795 | cid_658787
Type:
Small organic molecule
Emp. Form.:
C18H17ClN4
Mol. Mass.:
324.807
SMILES:
Clc1ccc2nc(nc(-c3ccccc3)c2c1)N1CCNCC1
Structure:
Search PDB for entries with ligand similarity: