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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM30862
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
198300±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM30862
Synonyms:
1-allyl-2,5-diketo-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carbonitrile | 1-allyl-2,5-dioxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carbonitrile | 2,5-bis(oxidanylidene)-1-prop-2-enyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carbonitrile | 2,5-dioxo-1-prop-2-enyl-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarbonitrile | 2,5-dioxo-1-prop-2-enyldipyrido[1,2-d:3',4'-f]pyrimidine-3-carbonitrile | MLS000094258 | SMR000029848 | cid_3239161
Type:
Small organic molecule
Emp. Form.:
C15H10N4O2
Mol. Mass.:
278.2655
SMILES:
C=CCn1c2nc3ccccn3c(=O)c2cc(C#N)c1=O
Structure:
Search PDB for entries with ligand similarity: