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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41653
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
>50000±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41653
Synonyms:
1-(2-pyridinyl)-3-thiophen-2-ylurea | 1-(2-pyridyl)-3-(2-thienyl)urea | 1-pyridin-2-yl-3-thiophen-2-yl-urea | 1-pyridin-2-yl-3-thiophen-2-ylurea | MLS000093554 | N-pyridin-2-yl-N'-thien-2-ylurea | SMR000029172 | cid_3243340
Type:
Small organic molecule
Emp. Form.:
C10H9N3OS
Mol. Mass.:
219.263
SMILES:
O=C(Nc1cccs1)Nc1ccccn1
Structure:
Search PDB for entries with ligand similarity: