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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41658
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
>50000±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41658
Synonyms:
1-(4-chlorophenyl)-N-(2-oxolanylmethyl)methanesulfonamide | 1-(4-chlorophenyl)-N-(oxolan-2-ylmethyl)methanesulfonamide | 1-(4-chlorophenyl)-N-(tetrahydro-2-furanylmethyl)methanesulfonamide | 1-(4-chlorophenyl)-N-(tetrahydrofurfuryl)methanesulfonamide | MLS000099995 | SMR000081216 | cid_2973451
Type:
Small organic molecule
Emp. Form.:
C12H16ClNO3S
Mol. Mass.:
289.778
SMILES:
Clc1ccc(CS(=O)(=O)NCC2CCCO2)cc1
Structure:
Search PDB for entries with ligand similarity: