Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41665
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
14470±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41665
Synonyms:
MLS000527145 | N-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-N'-(2,6-di-morpholin-4-yl-pyrimidin-4-yl)-hydrazine | N-[[5-(4-chlorophenyl)-2-furanyl]methylideneamino]-2,6-bis(4-morpholinyl)-4-pyrimidinamine | N-[[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-2,6-dimorpholin-4-yl-pyrimidin-4-amine | N-[[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-2,6-dimorpholin-4-ylpyrimidin-4-amine | SMR000117619 | [[5-(4-chlorophenyl)-2-furyl]methyleneamino]-(2,6-dimorpholinopyrimidin-4-yl)amine | cid_3112378
Type:
Small organic molecule
Emp. Form.:
C23H25ClN6O3
Mol. Mass.:
468.936
SMILES:
Clc1ccc(cc1)-c1ccc(CN=Nc2cc(nc(n2)N2CCOCC2)N2CCOCC2)o1 |w:13.14|
Structure:
Search PDB for entries with ligand similarity: