Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM45767
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC - Secondary Assay
IC50
3140±23100 nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC - Secondary Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM45767
Synonyms:
2-(3-morpholin-4-ylcarbonylphenyl)-1,2-benzothiazol-3-one | 2-[3-(morpholine-4-carbonyl)phenyl]-1,2-benzothiazol-3-one | 2-[3-[4-morpholinyl(oxo)methyl]phenyl]-1,2-benzothiazol-3-one | AB00540128 | cid_16749991
Type:
Small organic molecule
Emp. Form.:
C18H16N2O3S
Mol. Mass.:
340.396
SMILES:
O=C(N1CCOCC1)c1cccc(c1)-n1sc2ccccc2c1=O
Structure:
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