Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32270
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
13610±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32270
Synonyms:
6,7-dimethoxy-4-(2-oxolanylmethylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-(oxolan-2-ylmethylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-(tetrahydrofurfurylamino)-1H-quinazoline-2-thione | 6,7-dimethoxy-4-[(tetrahydrofuran-2-ylmethyl)amino]quinazoline-2(1H)-thione | MLS000045008 | SMR000026612 | cid_3243470
Type:
Small organic molecule
Emp. Form.:
C15H19N3O3S
Mol. Mass.:
321.395
SMILES:
COc1cc2nc(=S)[nH]c(NCC3CCCO3)c2cc1OC
Structure:
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