Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32325
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
2020±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32325
Synonyms:
1-(3-chlorophenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl)urea | 1-(3-chlorophenyl)-3-[2-(3-pyridinyl)-4-pyrimidinyl]urea | 1-(3-chlorophenyl)-3-[2-(3-pyridyl)pyrimidin-4-yl]urea | MLS000763594 | N-(3-chlorophenyl)-N'-[2-(3-pyridinyl)-4-pyrimidinyl]urea | SMR000337179 | cid_1488502
Type:
Small organic molecule
Emp. Form.:
C16H12ClN5O
Mol. Mass.:
325.752
SMILES:
Clc1cccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)c1
Structure:
Search PDB for entries with ligand similarity: