Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46414
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
4350±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46414
Synonyms:
4-(sec-butylthiocarbamoylamino)benzoic acid methyl ester | 4-[[(butan-2-ylamino)-sulfanylidenemethyl]amino]benzoic acid methyl ester | MLS000693126 | SMR000284763 | cid_3192433 | methyl 4-(butan-2-ylcarbamothioylamino)benzoate
Type:
Small organic molecule
Emp. Form.:
C13H18N2O2S
Mol. Mass.:
266.359
SMILES:
CCC(C)NC(=S)Nc1ccc(cc1)C(=O)OC
Structure:
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