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Target
Mucolipin-3
Ligand
BDBM46876
Substrate
n/a
Meas. Tech.
Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3)
EC50
12100±n/a nM
Citation
 PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay (2009)[AID] 
Target
Name:
Mucolipin-3
Synonyms:
MCLN3_HUMAN | MCOLN3 | MCOLN3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64244.09
Organism:
Homo sapiens (Human)
Description:
Q8TDD5
Residue:
553
Sequence:
MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK
  
Inhibitor
Name:
BDBM46876
Synonyms:
2-[methyl(tosyl)amino]acetic acid [(Z)-[amino-(3-nitrophenyl)methylene]amino] ester | 2-[methyl-(4-methylphenyl)sulfonylamino]acetic acid [(Z)-[amino-(3-nitrophenyl)methylidene]amino] ester | MLS000530876 | N'-[({methyl[(4-methylphenyl)sulfonyl]amino}acetyl)oxy]-3-nitrobenzenecarboximidamide | SMR000135854 | [(Z)-[amino-(3-nitrophenyl)methylidene]amino] 2-[methyl-(4-methylphenyl)sulfonylamino]acetate | [(Z)-[azanyl-(3-nitrophenyl)methylidene]amino] 2-[methyl-(4-methylphenyl)sulfonyl-amino]ethanoate | cid_9550114
Type:
Small organic molecule
Emp. Form.:
C17H18N4O6S
Mol. Mass.:
406.413
SMILES:
CN(CC(=O)ON=C(N)c1cccc(c1)[N+]([O-])=O)S(=O)(=O)c1ccc(C)cc1 |w:6.5|
Structure:
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