Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46596
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46596
Synonyms:
5-(2,5-dimethyl-1-pyrrolyl)-1,2-dihydro-1,2,4-triazole-3-thione | 5-(2,5-dimethylpyrrol-1-yl)-1,2-dihydro-1,2,4-triazole-3-thione | MLS-0079631.0001 | cid_9551136
Type:
Small organic molecule
Emp. Form.:
C8H10N4S
Mol. Mass.:
194.257
SMILES:
Cc1ccc(C)n1-c1n[nH]c(=S)[nH]1
Structure:
Search PDB for entries with ligand similarity: