Reaction Details Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM46038
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
1240±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM46038
Synonyms:
4-(3-keto-1,2-benzothiazol-2-yl)benzoic acid ethyl ester | 4-(3-oxo-1,2-benzothiazol-2-yl)benzoic acid ethyl ester | MLS-0315808.0001 | cid_2467794 | ethyl 4-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzoate | ethyl 4-(3-oxo-1,2-benzothiazol-2-yl)benzoate
Type:
Small organic molecule
Emp. Form.:
C16H13NO3S
Mol. Mass.:
299.344
SMILES:
CCOC(=O)c1ccc(cc1)-n1sc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: