Reaction Details Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM47035
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
1250±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM47035
Synonyms:
3-(4-methoxyphenyl)-2-phenyl-1,2,4-thiadiazol-2-ium-5-amine;hydrochloride | MLS-0390887.0001 | [3-(4-methoxyphenyl)-2-phenyl-1,2,4-thiadiazol-2-ium-5-yl]amine;hydrochloride | cid_25181257
Type:
Small organic molecule
Emp. Form.:
C15H14N3OS
Mol. Mass.:
284.356
SMILES:
COc1ccc(cc1)-c1nc(N)s[n+]1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: