Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47609
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
1222±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47609
Synonyms:
(3E)-2-amino-3-[(3-methoxyphenyl)hydrazinylidene]-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-one | (3E)-2-amino-3-[(3-methoxyphenyl)hydrazono]-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-one | (3E)-2-azanyl-3-[(3-methoxyphenyl)hydrazinylidene]-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-one | 2-amino-3-[(3-methoxyphenyl)diazenyl]-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9(4H)-one | MLS000705358 | SMR000231770 | cid_16189247
Type:
Small organic molecule
Emp. Form.:
C17H18N6O2
Mol. Mass.:
338.3638
SMILES:
COc1cccc(c1)N=Nc1c(N)[nH]n2c1nc1CCCCc1c2=O |w:9.10|
Structure:
Search PDB for entries with ligand similarity: