Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47660
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
567.4±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47660
Synonyms:
5-[(3-chlorobenzoyl)amino]-2-[(E)-2-(3,5-dimethylanilino)vinyl]-6-keto-pyran-3-carboxylic acid methyl ester | 5-[[(3-chlorophenyl)-oxomethyl]amino]-2-[(E)-2-(3,5-dimethylanilino)ethenyl]-6-oxo-3-pyrancarboxylic acid methyl ester | MLS000696059 | SMR000334964 | cid_5524030 | methyl 3-[(3-chlorobenzoyl)amino]-6-[(E)-2-(3,5-dimethylanilino)ethenyl]-2-oxo-2H-pyran-5-carboxylate | methyl 5-[(3-chlorobenzoyl)amino]-2-[(E)-2-(3,5-dimethylanilino)ethenyl]-6-oxopyran-3-carboxylate | methyl 5-[(3-chlorophenyl)carbonylamino]-2-[(E)-2-[(3,5-dimethylphenyl)amino]ethenyl]-6-oxidanylidene-pyran-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C24H21ClN2O5
Mol. Mass.:
452.887
SMILES:
COC(=O)c1cc(NC(=O)c2cccc(Cl)c2)c(=O)oc1CC=Nc1cc(C)cc(C)c1 |w:23.25|
Structure:
Search PDB for entries with ligand similarity: