Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM47674
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50
601.6±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay (2010)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM47674
Synonyms:
3-(3-chloro-4-methoxybenzyl)-4-imino-6,7-dimethoxy-3,4-dihydro-2(1H)-quinazolinethione | 4-amino-3-(3-chloro-4-methoxy-benzyl)-6,7-dimethoxy-quinazoline-2-thione | 4-amino-3-[(3-chloro-4-methoxyphenyl)methyl]-6,7-dimethoxy-2-quinazolinethione | 4-amino-3-[(3-chloro-4-methoxyphenyl)methyl]-6,7-dimethoxyquinazoline-2-thione | 4-azanyl-3-[(3-chloranyl-4-methoxy-phenyl)methyl]-6,7-dimethoxy-quinazoline-2-thione | MLS000720446 | SMR000335949 | cid_1489260
Type:
Small organic molecule
Emp. Form.:
C18H18ClN3O3S
Mol. Mass.:
391.872
SMILES:
COc1ccc(Cn2c(N)c3cc(OC)c(OC)cc3nc2=S)cc1Cl
Structure:
Search PDB for entries with ligand similarity: