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Target
Regulator of G-protein signaling 16
Ligand
BDBM47696
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
6560±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47696
Synonyms:
4-[(3-carbamoyl-4,5-dimethyl-2-thienyl)amino]-4-keto-butyric acid methyl ester | 4-[(3-carbamoyl-4,5-dimethyl-2-thiophenyl)amino]-4-oxobutanoic acid methyl ester | MLS000075656 | N-(3-Carbamoyl-4,5-dimethyl-thiophen-2-yl)-succinamic acid methyl ester | SMR000012612 | cid_649731 | methyl 4-[(3-aminocarbonyl-4,5-dimethyl-thiophen-2-yl)amino]-4-oxidanylidene-butanoate | methyl 4-[(3-carbamoyl-4,5-dimethylthiophen-2-yl)amino]-4-oxobutanoate
Type:
Small organic molecule
Emp. Form.:
C12H16N2O4S
Mol. Mass.:
284.331
SMILES:
COC(=O)CCC(=O)Nc1sc(C)c(C)c1C(N)=O
Structure:
Search PDB for entries with ligand similarity: