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Target
Regulator of G-protein signaling 16
Ligand
BDBM47705
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47705
Synonyms:
1-[2-(difluoromethoxy)-5-methyl-phenyl]-3-(2,4-dimethoxyphenyl)urea | 1-[2-(difluoromethoxy)-5-methylphenyl]-3-(2,4-dimethoxyphenyl)urea | 1-[2-[bis(fluoranyl)methoxy]-5-methyl-phenyl]-3-(2,4-dimethoxyphenyl)urea | MLS000097201 | N-[2-(difluoromethoxy)-5-methylphenyl]-N'-(2,4-dimethoxyphenyl)urea | SMR000076793 | cid_2208379
Type:
Small organic molecule
Emp. Form.:
C17H18F2N2O4
Mol. Mass.:
352.3326
SMILES:
COc1ccc(NC(=O)Nc2cc(C)ccc2OC(F)F)c(OC)c1
Structure:
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