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Target
Regulator of G-protein signaling 16
Ligand
BDBM42425
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM42425
Synonyms:
MLS000519757 | N-[1-(cyclohexylcarbamoyl)cyclohexyl]-N-(2-furfuryl)pyrazinamide | N-[1-(cyclohexylcarbamoyl)cyclohexyl]-N-(furan-2-ylmethyl)pyrazine-2-carboxamide | N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(2-furanylmethyl)-2-pyrazinecarboxamide | SMR000130175 | cid_4098324
Type:
Small organic molecule
Emp. Form.:
C23H30N4O3
Mol. Mass.:
410.5093
SMILES:
O=C(NC1CCCCC1)C1(CCCCC1)N(Cc1ccco1)C(=O)c1cnccn1
Structure:
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