Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48113
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
28000±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48113
Synonyms:
2-[[2-[[1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]amino]acetic acid ethyl ester | 2-[[2-[[1-(p-tolyl)pyrazolo[3,4-d]pyrimidin-4-yl]thio]acetyl]amino]acetic acid ethyl ester | MLS000032584 | SMR000013160 | [2-(1-p-Tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfanyl)-acetylamino]-acetic acid ethyl ester | cid_654950 | ethyl 2-[2-[1-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanylethanoylamino]ethanoate | ethyl 2-[[2-[1-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanylacetyl]amino]acetate
Type:
Small organic molecule
Emp. Form.:
C18H19N5O3S
Mol. Mass.:
385.44
SMILES:
CCOC(=O)CNC(=O)CSc1ncnc2n(ncc12)-c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: