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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48124
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
34300±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48124
Synonyms:
(4,8-dimethylquinazolin-2-yl)-[3-(3-morpholinopropyl)-2,4-dihydro-1H-s-triazin-6-yl]amine | 4,8-dimethyl-N-[3-(3-morpholin-4-ylpropyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]quinazolin-2-amine | 4,8-dimethyl-N-[3-[3-(4-morpholinyl)propyl]-2,4-dihydro-1H-1,3,5-triazin-6-yl]-2-quinazolinamine | MLS000084046 | SMR000047283 | cid_666009
Type:
Small organic molecule
Emp. Form.:
C20H29N7O
Mol. Mass.:
383.4906
SMILES:
Cc1cccc2c(C)nc(NC3=NCN(CCCN4CCOCC4)CN3)nc12 |t:11|
Structure:
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