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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM36973
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
15000±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM36973
Synonyms:
1-[[5-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]azepan-2-one | 1-[[5-[[5-(4-methylphenyl)-4-thieno[2,3-d]pyrimidinyl]thio]-1,3,4-oxadiazol-2-yl]methyl]-2-azepanone | 1-[[5-[[5-(p-tolyl)thieno[2,3-d]pyrimidin-4-yl]thio]-1,3,4-oxadiazol-2-yl]methyl]azepan-2-one | MLS000056603 | SMR000064688 | cid_2538553
Type:
Small organic molecule
Emp. Form.:
C22H21N5O2S2
Mol. Mass.:
451.564
SMILES:
Cc1ccc(cc1)-c1csc2ncnc(Sc3nnc(CN4CCCCCC4=O)o3)c12
Structure:
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