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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM36986
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
7720±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM36986
Synonyms:
1-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-2-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)thio]ethanone | 1-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-2-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone | 1-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-2-[[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]thio]ethanone | 1-(2,5-dimethyl-1-phenylpyrrol-3-yl)-2-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone | MLS000058356 | SMR000064018 | cid_2082388
Type:
Small organic molecule
Emp. Form.:
C20H17N3O2S2
Mol. Mass.:
395.498
SMILES:
Cc1cc(C(=O)CSc2nnc(o2)-c2cccs2)c(C)n1-c1ccccc1
Structure:
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