Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM38934
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
1220±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM38934
Synonyms:
MLS000058142 | N-[4-[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-oxidanylidene-ethyl]sulfanylphenyl]ethanamide | N-[4-[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-oxoethyl]sulfanylphenyl]acetamide | N-[4-[[2-[2,5-dimethyl-1-(2-thenyl)pyrrol-3-yl]-2-keto-ethyl]thio]phenyl]acetamide | N-[4-[[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)-3-pyrrolyl]-2-oxoethyl]thio]phenyl]acetamide | SMR000067575 | cid_2102349
Type:
Small organic molecule
Emp. Form.:
C21H22N2O2S2
Mol. Mass.:
398.542
SMILES:
CC(=O)Nc1ccc(SCC(=O)c2cc(C)n(Cc3cccs3)c2C)cc1
Structure:
Search PDB for entries with ligand similarity: