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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48128
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
8540±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48128
Synonyms:
MLS000057148 | N-[4-[2-[1-(2-methoxyethyl)-2,5-dimethyl-pyrrol-3-yl]-2-oxidanylidene-ethyl]sulfanylphenyl]ethanamide | N-[4-[2-[1-(2-methoxyethyl)-2,5-dimethylpyrrol-3-yl]-2-oxoethyl]sulfanylphenyl]acetamide | N-[4-[[2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl]thio]phenyl]acetamide | N-[4-[[2-keto-2-[1-(2-methoxyethyl)-2,5-dimethyl-pyrrol-3-yl]ethyl]thio]phenyl]acetamide | SMR000063999 | cid_2080432
Type:
Small organic molecule
Emp. Form.:
C19H24N2O3S
Mol. Mass.:
360.47
SMILES:
COCCn1c(C)cc(C(=O)CSc2ccc(NC(C)=O)cc2)c1C
Structure:
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