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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM37012
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
16100±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM37012
Synonyms:
(2E)-1-(5-chloranyl-2-methylsulfonyl-pyrimidin-4-yl)-2-(1,3,3-trimethylindol-2-ylidene)ethanone | (2E)-1-(5-chloro-2-mesyl-pyrimidin-4-yl)-2-(1,3,3-trimethylindolin-2-ylidene)ethanone | (2E)-1-(5-chloro-2-methylsulfonyl-4-pyrimidinyl)-2-(1,3,3-trimethyl-2-indolylidene)ethanone | (2E)-1-(5-chloro-2-methylsulfonylpyrimidin-4-yl)-2-(1,3,3-trimethylindol-2-ylidene)ethanone | MLS000055030 | SMR000065840 | cid_2320547
Type:
Small organic molecule
Emp. Form.:
C18H18ClN3O3S
Mol. Mass.:
391.872
SMILES:
CN1\C(=C\C(=O)c2nc(ncc2Cl)S(C)(=O)=O)C(C)(C)c2ccccc12
Structure:
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