Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48905
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00302±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48905
Synonyms:
2-amino-4-(3-thienyl)thiophene-3-carboxylic acid ethyl ester | 2-amino-4-(3-thiophenyl)-3-thiophenecarboxylic acid ethyl ester | 5-Amino-[3,3']bithiophenyl-4-carboxylic acid ethyl ester | MLS000070591 | SMR000008894 | cid_645868 | ethyl 2-amino-4-thiophen-3-ylthiophene-3-carboxylate | ethyl 2-azanyl-4-thiophen-3-yl-thiophene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C11H11NO2S2
Mol. Mass.:
253.341
SMILES:
CCOC(=O)c1c(N)scc1-c1ccsc1
Structure:
Search PDB for entries with ligand similarity: