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Target
D(1B) dopamine receptor
Ligand
BDBM48911
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.000661±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48911
Synonyms:
1-(5-Chloro-2-methoxy-phenyl)-2-(1-cyclopentyl-1H-tetrazol-5-ylsulfanyl)-ethanone | 1-(5-chloranyl-2-methoxy-phenyl)-2-[(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)sulfanyl]ethanone | 1-(5-chloro-2-methoxy-phenyl)-2-[(1-cyclopentyltetrazol-5-yl)thio]ethanone | 1-(5-chloro-2-methoxyphenyl)-2-(1-cyclopentyltetrazol-5-yl)sulfanylethanone | 1-(5-chloro-2-methoxyphenyl)-2-[(1-cyclopentyl-5-tetrazolyl)thio]ethanone | MLS000067965 | SMR000008181 | cid_651176
Type:
Small organic molecule
Emp. Form.:
C15H17ClN4O2S
Mol. Mass.:
352.839
SMILES:
COc1ccc(Cl)cc1C(=O)CSc1nnnn1C1CCCC1
Structure:
Search PDB for entries with ligand similarity: