Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48914
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.0254±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48914
Synonyms:
(E)-3-(1-cyclohex-3-enyl)-2-(1-methyl-2-benzimidazolyl)-2-propenenitrile | (E)-3-Cyclohex-3-enyl-2-(1-methyl-1H-benzoimidazol-2-yl)-acrylonitrile | (E)-3-cyclohex-3-en-1-yl-2-(1-methylbenzimidazol-2-yl)acrylonitrile | (E)-3-cyclohex-3-en-1-yl-2-(1-methylbenzimidazol-2-yl)prop-2-enenitrile | MLS000033517 | SMR000011469 | cid_5766869
Type:
Small organic molecule
Emp. Form.:
C17H17N3
Mol. Mass.:
263.337
SMILES:
Cn1c(nc2ccccc12)C(=C\C1CCC=CC1)\C#N |c:17|
Structure:
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