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Target
D(1B) dopamine receptor
Ligand
BDBM37640
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00452±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM37640
Synonyms:
MLS000079917 | N-(1-butyl-3-cyano-2-pyrrolo[3,2-b]quinoxalinyl)acetamide | N-(1-butyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)acetamide | N-(1-butyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)ethanamide | N-(1-butyl-3-cyanopyrrolo[3,2-b]quinoxalin-2-yl)acetamide | SMR000039760 | US9045483, 4 | cid_658861
Type:
Small organic molecule
Emp. Form.:
C17H17N5O
Mol. Mass.:
307.3498
SMILES:
CCCCn1c(NC(C)=O)c(C#N)c2nc3ccccc3nc12
Structure:
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