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Target
D(1B) dopamine receptor
Ligand
BDBM38950
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.0113±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM38950
Synonyms:
MLS000056567 | N-[2-(3,4-dimethoxyphenyl)ethyl]-5-(1-phenyltetrazol-5-yl)sulfanyl-1,3,4-thiadiazol-2-amine | N-[2-(3,4-dimethoxyphenyl)ethyl]-5-[(1-phenyl-1,2,3,4-tetrazol-5-yl)sulfanyl]-1,3,4-thiadiazol-2-amine | N-[2-(3,4-dimethoxyphenyl)ethyl]-5-[(1-phenyl-5-tetrazolyl)thio]-1,3,4-thiadiazol-2-amine | SMR000064679 | cid_2537704 | homoveratryl-[5-[(1-phenyltetrazol-5-yl)thio]-1,3,4-thiadiazol-2-yl]amine
Type:
Small organic molecule
Emp. Form.:
C19H19N7O2S2
Mol. Mass.:
441.53
SMILES:
COc1ccc(CCNc2nnc(Sc3nnnn3-c3ccccc3)s2)cc1OC
Structure:
Search PDB for entries with ligand similarity: