Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48955
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00331±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48955
Synonyms:
MLS000049620 | N'-(benzenesulfonyl)-N-(6-methoxy-4-pyrimidinyl)benzenecarboximidamide | N'-(benzenesulfonyl)-N-(6-methoxypyrimidin-4-yl)benzenecarboximidamide | N'-besyl-N-(6-methoxypyrimidin-4-yl)benzamidine | N-(6-methoxy-4-pyrimidinyl)-N'-(phenylsulfonyl)benzenecarboximidamide | N-(6-methoxypyrimidin-4-yl)-N'-(phenylsulfonyl)benzenecarboximidamide | SMR000076193 | cid_5648465
Type:
Small organic molecule
Emp. Form.:
C18H16N4O3S
Mol. Mass.:
368.41
SMILES:
COc1cc(N=C(NS(=O)(=O)c2ccccc2)c2ccccc2)ncn1 |w:5.4|
Structure:
Search PDB for entries with ligand similarity: