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Target
D(1A) dopamine receptor
Ligand
BDBM38278
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.0129±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM38278
Synonyms:
1-Benzyl-3-chloro-4-[(tetrahydro-furan-2-ylmethyl)-amino]-pyrrole-2,5-dione | 1-benzyl-3-chloro-4-(oxolan-2-ylmethylamino)pyrrole-2,5-dione | 1-benzyl-3-chloro-4-(tetrahydrofurfurylamino)-3-pyrroline-2,5-quinone | 3-chloranyl-4-(oxolan-2-ylmethylamino)-1-(phenylmethyl)pyrrole-2,5-dione | 3-chloro-4-(2-oxolanylmethylamino)-1-(phenylmethyl)pyrrole-2,5-dione | MLS000029274 | SMR000010759 | cid_650138
Type:
Small organic molecule
Emp. Form.:
C16H17ClN2O3
Mol. Mass.:
320.771
SMILES:
ClC1=C(NCC2CCCO2)C(=O)N(Cc2ccccc2)C1=O |c:1|
Structure:
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