Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM33071
Substrate
n/a
Meas. Tech.
Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay
IC50
11436.39864±n/a nM
Citation
 PubChem, PC Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM33071
Synonyms:
2,3-Di-furan-2-yl-quinoxaline-6-carboxylic acid (2-hydroxy-ethyl)-amide | 2,3-bis(2-furanyl)-N-(2-hydroxyethyl)-6-quinoxalinecarboxamide | 2,3-bis(2-furyl)-N-(2-hydroxyethyl)quinoxaline-6-carboxamide | 2,3-bis(furan-2-yl)-N-(2-hydroxyethyl)quinoxaline-6-carboxamide | MLS000529296 | SMR000121771 | cid_3157644
Type:
Small organic molecule
Emp. Form.:
C19H15N3O4
Mol. Mass.:
349.3401
SMILES:
OCCNC(=O)c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: