Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51465
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
375±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51465
Synonyms:
Isoxazole-5-carboxylic acid methyl-(5-pyridin-2-yl-[1,3,4]thiadiazol-2-yl)-amide | MLS000075499 | N-methyl-N-(5-pyridin-2-yl-1,3,4-thiadiazol-2-yl)-1,2-oxazole-5-carboxamide | N-methyl-N-[5-(2-pyridinyl)-1,3,4-thiadiazol-2-yl]-5-isoxazolecarboxamide | N-methyl-N-[5-(2-pyridyl)-1,3,4-thiadiazol-2-yl]isoxazole-5-carboxamide | SMR000000571 | cid_652845
Type:
Small organic molecule
Emp. Form.:
C12H9N5O2S
Mol. Mass.:
287.297
SMILES:
CN(C(=O)c1ccno1)c1nnc(s1)-c1ccccn1
Structure:
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