Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM30909
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
403±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM30909
Synonyms:
3-benzyl-6-chloro-8-[(dimethylamino)methyl]-7-hydroxy-4-methyl-2H-chromen-2-one | 3-benzyl-6-chloro-8-[(dimethylamino)methyl]-7-hydroxy-4-methyl-coumarin | 3-benzyl-6-chloro-8-[(dimethylamino)methyl]-7-hydroxy-4-methylchromen-2-one | 6-chloranyl-8-[(dimethylamino)methyl]-4-methyl-7-oxidanyl-3-(phenylmethyl)chromen-2-one | 6-chloro-8-[(dimethylamino)methyl]-7-hydroxy-4-methyl-3-(phenylmethyl)-1-benzopyran-2-one | MLS000097166 | SMR000076723 | cid_5429720
Type:
Small organic molecule
Emp. Form.:
C20H20ClNO3
Mol. Mass.:
357.831
SMILES:
CN(C)Cc1c(O)c(Cl)cc2c(C)c(Cc3ccccc3)c(=O)oc12
Structure:
Search PDB for entries with ligand similarity: