Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51572
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
461±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51572
Synonyms:
6-chloranyl-8-[(dimethylamino)methyl]-3-ethyl-4-methyl-7-oxidanyl-chromen-2-one | 6-chloro-8-[(dimethylamino)methyl]-3-ethyl-7-hydroxy-4-methyl-1-benzopyran-2-one | 6-chloro-8-[(dimethylamino)methyl]-3-ethyl-7-hydroxy-4-methyl-2H-chromen-2-one | 6-chloro-8-[(dimethylamino)methyl]-3-ethyl-7-hydroxy-4-methyl-coumarin | 6-chloro-8-[(dimethylamino)methyl]-3-ethyl-7-hydroxy-4-methylchromen-2-one | MLS000050086 | SMR000077117 | cid_5739939
Type:
Small organic molecule
Emp. Form.:
C15H18ClNO3
Mol. Mass.:
295.761
SMILES:
CCc1c(C)c2cc(Cl)c(O)c(CN(C)C)c2oc1=O
Structure:
Search PDB for entries with ligand similarity: