Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51760
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
785±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51760
Synonyms:
5-[2-(4-methoxyphenyl)-3-[2-(4-methoxyphenyl)ethynyl]-1-benzofuran-5-yl]-1,3-benzodioxole | 5-[2-(4-methoxyphenyl)-3-[2-(4-methoxyphenyl)ethynyl]-5-benzofuranyl]-1,3-benzodioxole | 5-[2-(4-methoxyphenyl)-3-[2-(4-methoxyphenyl)ethynyl]benzofuran-5-yl]-1,3-benzodioxole | MLS001144022 | SMR000526344 | cid_24747925
Type:
Small organic molecule
Emp. Form.:
C31H22O5
Mol. Mass.:
474.5034
SMILES:
COc1ccc(cc1)C#Cc1c(oc2ccc(cc12)-c1ccc2OCOc2c1)-c1ccc(OC)cc1
Structure:
Search PDB for entries with ligand similarity: