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Target
Beta-lactamase
Ligand
BDBM51980
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
4731±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51980
Synonyms:
4-butyl-3-(3-methyl-2-thienyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(3-methylthiophen-2-yl)-1H-1,2,4-triazole-5-thione | 4-butyl-5-(3-methyl-2-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide | MLS000704121 | SMR000228258 | cid_1768080
Type:
Small organic molecule
Emp. Form.:
C11H15N3S2
Mol. Mass.:
253.387
SMILES:
CCCCn1c(n[nH]c1=S)-c1sccc1C
Structure:
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