Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM51998
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
1004±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51998
Synonyms:
1-(1-cyclohex-3-enylmethylideneamino)-3-[3-(dimethylsulfamoyl)phenyl]thiourea | 1-(cyclohex-3-en-1-ylmethyleneamino)-3-[3-(dimethylsulfamoyl)phenyl]thiourea | 1-(cyclohex-3-en-1-ylmethylideneamino)-3-[3-(dimethylsulfamoyl)phenyl]thiourea | MLS001002365 | SMR000368888 | cid_4020866
Type:
Small organic molecule
Emp. Form.:
C16H22N4O2S2
Mol. Mass.:
366.501
SMILES:
CN(C)S(=O)(=O)c1cccc(NC(=S)NN=CC2CCC=CC2)c1 |w:15.14,c:20|
Structure:
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