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Target
Beta-lactamase
Ligand
BDBM51951
Substrate
n/a
Meas. Tech.
Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
IC50
59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM51951
Synonyms:
MLS000097889 | N-(amino-keto-phenyl-persulfuranylidene)carbamic acid ethyl ester | N-(amino-oxo-phenyl--sulfanylidene)carbamic acid ethyl ester | SMR000060035 | cid_2999456 | ethyl N-(amino-oxo-phenyl--sulfanylidene)carbamate | ethyl N-(azanyl-oxidanylidene-phenyl--sulfanylidene)carbamate
Type:
Small organic molecule
Emp. Form.:
C9H12N2O3S
Mol. Mass.:
228.268
SMILES:
CCOC(=O)N=S(N)(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: